Clinical trials: Uneven skin tone clinical trial
In 2005, Union-Swiss commissioned a 12-week clinical assessment to test the effect of the topical application of Bio-Oil on the appearance of uneven skin tone. This was conducted from September to December 2005 by the Photobiology Laboratory of the Medical University of South Africa - an internationally recognized clinical test laboratory that over the past 15 years, has conducted clinical studies for most of the major multinational cosmetic and toiletry companies.
Methodology
- 30 panelists: 15 Caucasian and 15 Black African - all female between the ages of 18 and 55.
- Application: twice daily.
- All sites were facial Melasma. Melasma is a skin condition presenting as brown patches found on the faces of some women and thought to be related to hormonal changes (e.g. from pregnancy or use of oral contraceptives). Once evident, it persists after the initiating hormonal change and is aggravated by exposure to ultra-violet light.
- Bilateral dark patches were chosen to enable a half-face/neck study design, allowing for intra-subject comparison.
- From week 0 to week 8 the clinician noted an equal improvement for both the Caucasian and Black African women. However from week 8 to week 12 the Black African women showed an increased improvement.
